Category: Uncategorized
-
LONGEVITY
FOXO Signaling and Cellular Senescence
How the FOXO family of transcription factors regulates the survival of senescent cells, and the implications for senolytic drug development.
May 12, 2026 -
RECOVERY & REPAIR
Mechanisms of Tissue Repair: Beyond BPC-157
A look at how the peptide tissue-repair field is expanding beyond BPC-157 to include thymosin fragments, copper peptides, and engineered growth-factor mimetics.
May 7, 2026 -
METABOLIC HEALTH
Systems Biology of Metabolic Adaptation
How modern multi-omics methods are reframing our understanding of metabolic adaptation as a coordinated systems response rather than a set of isolated tissue responses.
May 4, 2026 -
PK Methodology in Peptide Research
A primer on how the pharmacokinetic principles that govern small-molecule drug development apply (and don't apply) to peptide therapeutics.
May 1, 2026 -
LONGEVITY
METABOLIC HEALTH
Modeling Mitochondrial Dynamics in Aging
A look at how perturbations in mitochondrial fission, fusion, and mitophagy contribute to age-related metabolic decline and what experimental systems best capture them.
Apr 29, 2026 -
LONGEVITY
METABOLIC HEALTH
MOTS-c: Mitochondrial-to-Nuclear Signaling and Metabolic Adaptation
A review of how mitochondrial-derived peptides such as MOTS-c bridge organelle and nuclear signaling to coordinate adaptive responses to metabolic stress.
Apr 26, 2026 -
COGNITIVE FUNCTION
Nootropic Peptides and Neuroprotection: Mechanisms and Clinical Potential
A survey of the emerging class of synthetic neuroactive peptides, focusing on the shared BDNF-elevating, monoaminergic, and neurotrophic mechanisms that distinguish them from small-molecule…
Apr 23, 2026 -
LONGEVITY
Epitalon and Telomerase Activation Research
A critical review of the evidence that Epitalon induces telomerase reverse transcriptase expression, with attention to replication status outside the original Russian research network.
Apr 19, 2026 -
RECOVERY & REPAIR
BPC-157: Mechanisms of Tissue Repair and Regeneration
An overview of the preclinical evidence for BPC-157's role in angiogenesis-driven tissue regeneration, with particular attention to the VEGF, eNOS, and growth-hormone receptor pathways.
Apr 15, 2026 -
METABOLIC HEALTH
GLP-1 Receptor Agonists and Metabolic Adaptation
A comprehensive review of how GLP-1 receptor agonists drive sustained changes in appetite regulation, insulin sensitivity, and energy balance through coordinated CNS, pancreatic, and…
Apr 8, 2026